We examine the ethical, philosophical and legal questions raised by AI in neuroscience and neurosurgery, and lead frameworks, including the Declaration of Sydney, for using it responsibly.

Neuro-ethics, Neurophilosophy & Neuro-laws is the lab's commitment to advancing computational neuroscience responsibly. As AI reaches deeper into diagnosis, imaging and the operating theatre, it raises questions that are not merely technical, about safety, accountability, transparency, consent and the proper role of automated judgement in high-stakes care. The lab's flagship contribution in this domain is the Declaration of Sydney, a framework of principles for the ethical use of artificial intelligence in neurosurgery, for which the lab's director is corresponding author. Around it, our work engages with the philosophy of mind and machine, the legal implications of clinical AI, and the practical governance needed to deploy these tools safely. This domain runs through everything the lab does. It is the assurance that speed and capability never come at the cost of the patient's interest, that as computation transforms neurosurgical care, it does so on principled foundations.