Operative

Computational Neurosurgery

Bringing computation into the operating theatre.

Overview

From fluorescence-guided resection to connectomics and surgical corridor planning, we bring computation into the operating theatre to make brain surgery safer, more precise and more personalised.

Computational Neurosurgery is the founding vision of the lab, the first of its kind in Australia, and it sits at the point where computational science meets the operating theatre. We develop tools that help neurosurgeons see more, plan better and operate more safely, translating data and algorithms into decisions made at the bedside and on the table. Our work spans intraoperative guidance, including fluorescence-guided resection; physics-based and computational planning of surgical corridors that minimise disruption to eloquent tissue; and connectomics approaches that map the brain's networks to inform pre- and intra-operative decisions. Across these, the goal is the same: to reduce risk and improve outcomes by giving surgeons quantitative, patient-specific information. The lab also leads on the responsible foundations of this field. As corresponding contributors to the Declaration of Sydney, a framework for the ethical use of AI in neurosurgery, we work to ensure that computational neurosurgery advances safely, transparently and in the patient's interest.

Methods

Techniques & approaches

The computational methods that underpin this research area

Radiomics

Fluorescence-guided surgery, Surgical corridor planning, Connectomics, Intraoperative guidance, Neuronavigation

Publications

Selected publications in this area

Journal article

2024

Adaptive Clustering for EGFR Amplification Prediction in Glioblastoma: A Variational Autoencoder-Dirichlet Bayesian Gaussian Approach

Danaei Mehr H., Cong C., Noorani I., Di Ieva A., Liu S.

Pain Practice

Book chapter

2024

Computational neurosurgery: Foundation

Di Ieva A., Suero Molina E., Liu S., Russo C.

Computational neurosurgery

Review

2024

Cortical and Subcortical Stimulation for Pain: Network Mechanisms and Therapeutic Implications

George Rudd, Antonio Di Ieva

Neuroscientist

Book chapter

2024

Neurosurgery, explainable AI, and legal liability

Matulionyte R., Suero Molina E., Di Ieva A.

Computational neurosurgery

Funding

Selected funding in this area

Grants supporting our computational neuroimaging research programme

NHMRC

Computational modelling of aneurysm rupture

$724,101

Project Grant

Abbott; B Braun

CNS Lab Computational Neurosurgery Fellowship

$600,000

Industry sponsorship

Industry sponsors

1st World Conference of Computational Neurosurgery (WCCNS)

$260,000

Conference sponsorship

RACS

John Mitchell Crouch Fellowship: founding the CNS Lab

$150,000

John Mitchell Crouch Fellowship

Browse publications.

Join our work.

Explore the full body of CNS Lab research or contact us to discuss collaboration opportunities.