Operative

Computational Neurosurgery

Bringing computation into the operating theatre.

Overview

From fluorescence-guided resection to connectomics and surgical corridor planning, we bring computation into the operating theatre to make brain surgery safer, more precise and more personalised.

Computational Neurosurgery is the founding vision of the lab, the first of its kind in Australia, and it sits at the point where computational science meets the operating theatre. We develop tools that help neurosurgeons see more, plan better and operate more safely, translating data and algorithms into decisions made at the bedside and on the table. Our work spans intraoperative guidance, including fluorescence-guided resection; physics-based and computational planning of surgical corridors that minimise disruption to eloquent tissue; and connectomics approaches that map the brain's networks to inform pre- and intra-operative decisions. Across these, the goal is the same: to reduce risk and improve outcomes by giving surgeons quantitative, patient-specific information. The lab also leads on the responsible foundations of this field. As corresponding contributors to the Declaration of Sydney, a framework for the ethical use of AI in neurosurgery, we work to ensure that computational neurosurgery advances safely, transparently and in the patient's interest.

Methods

Techniques & approaches

The computational methods that underpin this research area

Radiomics

Fluorescence-guided surgery, Surgical corridor planning, Connectomics, Intraoperative guidance, Neuronavigation

Publications

Selected publications in this area

Book chapter

2024

Fractal-based analysis of arteriovenous malformations (AVMs)

Di Ieva A., Reishofer G.

The fractal geometry of the brain

Journal article

2024

Adaptive Clustering for EGFR Amplification Prediction in Glioblastoma: A Variational Autoencoder-Dirichlet Bayesian Gaussian Approach

Danaei Mehr H., Cong C., Noorani I., Di Ieva A., Liu S.

Pain Practice

Conference paper

2024

Molecular and genetic markers to predict clinical behaviour and recurrence in craniopharyngiomas: a systematic review

Nicholas M., Di Ieva A., Preda V.

ENDO 2023 - Chicago, United States

Letter

2024

Letter to the Editor Regarding The Exoscope in Neurosurgery: An Innovative Point of View. A Systematic Review of the Technical, Surgical, and Educational Aspects

Ieva A.D., Tschabitscher M.

World Neurosurgery

Funding

Selected funding in this area

Grants supporting our computational neuroimaging research programme

NHMRC

Computational modelling of aneurysm rupture

$724,101

Project Grant

Abbott; B Braun

CNS Lab Computational Neurosurgery Fellowship

$600,000

Industry sponsorship

Industry sponsors

1st World Conference of Computational Neurosurgery (WCCNS)

$260,000

Conference sponsorship

RACS

John Mitchell Crouch Fellowship: founding the CNS Lab

$150,000

John Mitchell Crouch Fellowship

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Join our work.

Explore the full body of CNS Lab research or contact us to discuss collaboration opportunities.